Focused on Veterinary Diagnostics
Focused on Veterinary Diagnostics

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  • > MegaELISA® EHRLICHIA canis

    Applicable to

    Dog

    MegaELISA® EHRLICHIA canis
    > Field of Application

    MegaELISA® EHRLICHIA canis is an enzyme immunoassay for the qualitative detection of IgG antibodies against Ehrlichia canis in plasma or serum of the dog.

    > General

    Canine monocytic ehrlichiosis (CME) is caused by the rickettsia Ehrlichia canis, which are mainly transmitted by the brown dog tick (Rhipicephalus sanguineus). Ehrlichia canis is found in many parts of the world, especially in the Mediterranean area, but also in Switzerland and partly Germany. Ehrlichiosis is common in the dog, but seldom in humans.

    The concentration of specific antibodies increases sharply 2–3 weeks post infection. A fourfold titre increase of antibodies in an interval of two weeks (seroconversion) is indicative for an acute infection. In the acute stage, the dog shows apathy, anorexia, fever and lymphadenitis. In the subclinical phase, clinical symptoms are missing, but not the typical ehrlichiosis laboratory results like hyperglobulinaemia and thrombocytopenia. Chronic phase animals show slight up to life-threatening symptoms: spontaneous bleedings, neurological disorders, anaemia, severe loss of weight as well as spleno- and hepatomegaly. Indirect antibody detection is known to be an important diagnostic tool diagnosing CME beside clinical symptoms, case history (travel abroad) and direct antigen detection.

    MegaELISA® EHRLICHIA canis is based on highly specific E. canis antigens for a fast and reliable detection of antibodies against Ehrlichia canis in plasma or serum of infected dogs.

    Specifications

    Detection of

    Antibodies

    Sample material:

    Plasma or serum

    Test time/duration

    125 minutes

    Storage

    2–8°C

    Sensitivity

    95.7%

    Specificity

    97.9%

    Comparison method

    IFAT

    Test procedure

    ELISA

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    Product

    Art.-No. 991096EK1

    request> Into the basket

    Format:

    1 test-kit contains 96 determinations (12 test strips with 8 determinations each)

    Product

    Art.-No. 991048EK1

    request> Into the basket

    Format:

    1 test-kit contains 48 determinations (6 test strips with 8 determinations each)