Focused on Veterinary Diagnostics
Focused on Veterinary Diagnostics

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  • > FASTest® CDV-CPV Ab

    Applicable to

    Dog

    FASTest® CDV-CPV Ab

    > Test principle

    > Service

    Professor em. Richard Ford Discusses How Maternal Antibodies Interfere With Core Vaccines

    > Field of Application

    FASTest® CDV-CPV Ab is a rapid immunochromatographic assay for the qualitative detection of antibodies against the Canine Distempervirus and the Canine Parvovirus in whole blood, plasma or serum of the dog.

    > General

    Antibodies are basic modules of the humoral immune response. They are passed by passively via the colostrum as so-called maternal antibodies (mAb) onto the yet immunoincompetent newborns or induced actively by natural field infection or vaccination. The antibody titre is varying individually in each animal, depending on multiple factors.The titre can persist over an extended period of time, partially lifelong, in efficient protection concentration (= reliable immunity by protective antibodies) or can fall below the efficient protection concentration (non-reliable immunity) in the course of time.

    Depending on the level of individual antibody titre, the veterinarian is able to decide fast and reliable the necessity of vaccination or nonvaccination due to following questions:

    Individual vaccination point of the breeding bitch. In problematic breedings, the determination of antibody status of the female makes sense during pregnancy to decide whether a booster vaccination before birth is necessary or to find the optimal primary vaccination time of the puppies.

    Individual vaccination point of the puppies: Primary vaccination. There is a critical stage (so-called immunity gap) in puppies, especially in the first 12–16 weeks. During this stage the concentration of mAb could be high enough to inactivate the vaccinating virus but also too low to protect from field infection. Therefore it is important to find the individual primary vaccination point for each puppy to guarantee an appropriate protection.

    For the determination of antibody status of the whole litter, it is possible to determine the antibody status of only one puppy, representative for the other puppies (so-called “fraternal antibody titre”). Here, the balanced colostrum assumption or development of all puppies is absolutely necessary.

    Booster vaccination. By determination of the actual antibody status, an individual decision of the necessity of booster vaccination of the puppy or the adult animal can be made.

    Being fast, safe and reliable, for pet owner and breeder these important questions can be answered practically by FASTest® CDV-CPV Ab. This enables the veterinarian an appropriate and customized vaccination diagnostics and strategy, adapted to dog and pet owner.

    Specifications

    Detection of

    Antibodies

    Sample material:

    Whole blood, plasma or serum

    Test time/duration

    10 minutes

    Storage

    Room temperature (15–25°C)

    Sensitivity

    CDV Ab: 99.9 %
    CPV Ab: 99.9 %

    Specificity

    CDV Ab: 99.8 %
    CPV Ab: 99.4 %

    Comparison method

    CDV Ab: Serum neutralisation test; CPV Ab: Hemagglutination inhibition test

    Test procedure

    Rapid test

    Tab-Container Desktop

    Product

    Art.-No. 821024RK1

    request> Into the basket

    Format:

    1 package contains 12 test-kits with 2 double test cassettes each

    Product

    Art.-No. 821010RK1

    request> Into the basket

    Format:

    1 test-kit with 10 double test cassettes