Professor em. Richard Ford Discusses How Maternal Antibodies Interfere With Core Vaccines
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> FASTest® CDV-CPV Ab
Applicable to
Dog
> Field of ApplicationFASTest® CDV-CPV Ab is a rapid immunochromatographic assay for the qualitative detection of antibodies against the Canine Distempervirus and the Canine Parvovirus in whole blood, plasma or serum of the dog.
> GeneralAntibodies (Ab) are basic modules of the humoral immune response. They are passed by passively via the colostrum as so-called maternal antibodies (mAb) onto the yet immunoincompetent newborns or induced actively by natural field infection or vaccination. The ab titre is varying individually in each animal, depending on multiple factors. The titre can persist over an extended period of time, partially lifelong, in efficient protection concentration (= reliable immunity by protective abs) or can fall below the efficient protection concentration (non-reliable immunity) in the course of time. Depending on presence or NON-presence of abs in the sample, the veterinarian can make a quick and reliable decision regarding the necessity of “vaccination or not?” in the following questions.
According to the opinion of the German Standing Vaccination Commission for Veterinary Medicine (StIKo Vet) on Ab testing*, after active immunization and / or field infection (active immune response with Ab formation), every titre is protective or no titre is an indication for immediate vaccination.
Testing of field-infected or completely vaccinated animals
– before planned routine vaccination (“titre check”)
Testing of puppies
1. to estimate the appropriate point in time for the first immunization (1st primary immunization): Screening using FASTest® CDV-CPV Ab is possible. According to the StIKo Vet statement, semi-quantitative rapid test results should be confirmed using SN titre (CDV) or HAI (CPV) in order to determine the quantitative titre.
2. to determine the optimal vaccination time point of a litter, it is possible to determine the maternal ab status representatively for the other puppies (so-called “fraternal ab titre”). For this purpose, a FASTest® CDV-CPV Ab must be performed on at least two randomly selected puppies per litter.
3. to check the success of a basic immunization as early as possible from the 6th month of life.
Being fast, safe and reliable, for pet owner and breeder these important questions can be answered practically by FASTest® CDV-CPV Ab. This enables the veterinarian an appropriate and customized vaccination diagnostics and strategy, adapted to dog and pet owner.
Specifications
Detection of
Antibodies
Sample material:
Whole blood, plasma or serum
Test time/duration
10 minutes
Storage
Room temperature (15–25°C)
Sensitivity
CDV Ab: 99.9 %
CPV Ab: 99.9 %Specificity
CDV Ab: 99.8 %
CPV Ab: 99.4 %Comparison method
CDV Ab: Serum neutralisation test; CPV Ab: Hemagglutination inhibition test
Test procedure
Rapid test
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