19.10.2015 - New MEGACOR IgG rapid test for foals
Qualitative detection of IgG antibodies
FASTest® IgG equine is an immunochromatographic rapid test for the qualitative detection of IgG antibodies in whole blood, plasma or serum of the foal.
The humoral immune defence is guaranteed by the formation of blood soluble antibodies (immunoglobulins). The immunoglobulins G (IgG, gamma globulins) belong to the antibody class G mainly directed against viruses and bacteria.
An inadequate transfer of colostral IgG onto the foal is one of the most important predisposing factors for infectious foal diseases in the neonate phase. Consequence of partial (IgG: 4 to 8 mg/ml) to complete failure (IgG < 4 mg/ml) of passive transfer (FPT) often are septicaemias, causing 50% of all foal losses in the first week of age.
The optimal time slot for foals is 8 (risk foals) to 24 hours post natum. FASTest® IgG equine enables the veterinarian on-site, without any technical costs and within 10 minutes to confirm a suspicion for FPT in the foal.
Please find further information here.
Instructions for use
13.10.2015 - Cryptosporidiosis
In a PCR study about cryptosporidiosis in a horse clinic with foal intensive care boxes, a prevalence of 37.8 % was determined. This is clearly higher than in horse stud farms (1-21 %). The authors conclude that intensive care foal boxes seem to support the spread of cryptosporidiosis.
The FASTest® CRYPTO Strip enables the veterinarian a fast and reliable on-site diagnostics and therefore rapid therapeutic and prophylactic measures for animal and man (zoonosis!).
- Tierärztliche Praxis Großtiere - Kompendium - 4/2015: Jennifer Nieth, S. 250
- Galuppi R et al. Epidemical survey on Cryptosoridium in an Equine Perinatology Unit. Vet Parasitology 2015; 210: 10-18
17.09.2015 - New: Storage at room temperature
MYKODERMOASSAY TRIO ad us. vet.
DERMATOPHYTOSIS – highly infectious skin disease with zoonotic potential
for the detection of veterinary relevant dermatophytes in pocket pets, pets and farm animals
Can now be stored at room temperature!
13.08.2015 - New: MegaPCR® for Veterinarian and Laboratory
With its new product line MegaPCR® VET, MEGACOR Diagnostik GmbH extends its veterinary medicinal in vitro diagnostics range. Herewith, veterinarians and laboratories are steeled for future challenges in veterinary diagnostics.
- Test-kit for POCKIT™ device, ready-to-use
- The compact PCR for beginners
- Veterinary practice / veterinary hospital
- Veterinary laboratory without experience in PCR
- Test-kit for all established PCR laboratory cyclers
- taco™ extraction device: fully automated DNA purification
- PetNAD™ extraction kit: manual DNA purification
MegaPCR® VET are validated test-kits that can be handled on all common cyclers as well as the newly developed POCKIT™. The POCKIT™ is based on iiPCR and allows PCR newcomers to perform the PCR on-site within one hour. The attractively priced POCKIT™ is suitable for both: laboratories as well as veterinarians, and it also withstands the examination by OIE.
Thereby, both laboratories as well as veterinarians take the lead in diagnostics.
If you have further questions, do not hesitate to contact us! www.megacor.com
Flyer MegaPCR® VET
29.07.2015 - Correlation between leucocyte number and CRP value
A study with 924 dogs revealed no correlation between the leucocyte number and the C-reactive protein (CRP). The leucocyte number can be influenced by various pathologic and physiologic factors, so that with acute inflammation increased CRP values can be seen both with physiological and pathological leucocyte numbers (leucocytosis / leucopenia). On the contrary, the value of CRP concentration reflects the intensity of inflammation as well as its persistence.
Through its low physiological basal concentration, its rapid increase (10-100 fold) already 4h after beginning of the inflammatory stimulus, its peak concentration after 24 h as well as its decrease 48 h after the end of the inflammatory stimulus, the CRP determination as marker of an inflammatory event is a valuable diagnostic component in daily routine.
The FASTest® CRP canine enables the veterinarian to have a simple, rapid and on-site decision whether an inflammatory process is going on or not. Therefore, the initiation of further diagnostic or therapeutic measures on-site is possible.
Kleintierpraxis 60, Heft 7 (2015): Untersuchungen zur CRP-Konzentration bei verschiedenen Leukozytenkonzentrationen: D.Breu, S.Klenner, E. Müller: S. 349-357.
17.04.2015 - FASTest® CRYPTO Strip
A study with 120 snake feces samples of various species showed that the presence of reptile specific Cryptosporidia is rather marginal. More often, C. parvum (zoonosis) and C. muris (feeding with infected prey) were detected.
To exclude possible consequences for human health, reptile stocks should be tested regularly for Cryptosporidia, especially Cryptosporidium parvum.
Source: Kleintierpraxis 60, Heft 4 (2015)
Cryptosporidium bei Heimtierschlangen in Italien: Molekulare Charakterisierung und zoonotische Konsequenzen; Vet Parasitol 197 (1-2): 68-73
12.02.2015 - Giardia duodenalis in dog and cat
Another actual study* confirms the suspicion that dogs and cats are carriers of the human pathogen genotypes (assemblages) A and B.
Therefore, a Giardia infection in dog and cat must be seen as potential zoonotic. To prove the infectious cysts, in principle dogs with intermittent or chronic diarrhoea symptoms should be tested according to the capc.vet guide lines. Due to intermittent cyst shedding, a single negative test result does not exclude a persistent Giardia infection. Hence, with current diarrhoea symptoms and negative test result, a test repetition ca. 1 week later with a fecal sample from 3 consecutive days or of three sequential feces sample is reasonable. Only a repeatedly negative test result can exclude a Giardia infection definitely.
*Literature: V34 Giardia duodenalis bei Hunden und Katzen: eine epidemiologische Studie; S. Rehbein, C. Klotz, E. Müller, A. Aebischer, B. Kohn; 23. Jahrestagung der FG „Innere Medizin und klinische Labordiagnostik“ der DVG (InnLab), 23./24. Januar 2015 in Leipzig, Schattauer Tierärztliche Praxis Kleintiere 1/2015
06.02.2015 - Titre Check before CPV vaccination via FASTest® CPV Ab
Does your patient have a good immunity (adequate antibody titre) against the Canine Parvovirus? From which titre before vaccination, a booster vaccination makes sense?
Although an actual study shows that the German dog population is protected well against Parvovirus, however, many dogs do not react with an appropriate antibody increase after vaccination. Dogs showing a non-protective antibody titre during titre check do react significantly more frequently with an adequate titre increase.
To guarantee an adequate titre increase after vaccination, the verification of the antibody status is highly recommended.
Literature: V35 Prävalenz von Antikörpern gegen kanine Parvoviren und Reaktion auf Wiederholungsimpfung bei gesunden Hunden: M. Riedl, U. Truyen, K. Hartmann; 23. Jahrestagung der FG „Innere Medizin und klinische Labordiagnostik“ der DVG (InnLab), 23./24. Januar 2015 in Leipzig, Schattauer Tierärztliche Praxis Kleintiere 1/2015
03.02.2015 - Diarrhoea in the cat
Despite of the main appearance of Giardia duodenalis single infections (FASTest® GIARDIA Strip), co-infections with Tritrichomonas foetus (InPouchTM TF-Feline) are not seldom.
Therefore, especially in case of "treatment failure for Giardia", an additional tritrichomonads diagnostics with InPouchTM TF-Feline should be done to verify an infection with T. foetus.
Literatur: P03 Giardia duodenalis – Koinfektionen mit Tritrichomonas foetus bei Katzen: J. Csokai, E. M. Sicking, E. Müller; 23. Jahrestagung der FG „Innere Medizin und klinische Labordiagnostik“ der DVG (InnLab), 23./24. Januar 2015 in Leipzig, Schattauer Tierärztliche Praxis Kleintiere 2/2015
15.11.2014 - paraTEST® VET - Flotation diagnosis system
paraTEST® VET is a simple, hygienic and standardised parasite diagnosis system for the microscopical proof of parasite eggs and oocysts from the feces of pocket pets, pets and farm animals.
The flotation method is a long-standing coproscopical detection method in the veterinary medicine. The paraTEST® VET system allows the uptake of an adequate amount of feces with help of the blue sieve insert, its hygienical keeping in the paraTEST® VET analysis box as well as, if needed, the transport into the veterinary laboratory. By addition of the flotation solution with high specifical weight, the parasite eggs searched for flotate to the surface of the forming convex meniscus and settle to the bottom of the cover slip on the meniscus after ca. 15 minutes. This cover slip can then be analysed with a microscope by trained personnel for the presence of parasite eggs.
paraTEST® VET is therefore perfectly suitable for the on-site parasite diagnosis. The rapid detection of the various parasite stadiums gives the veterinarian the possibility to initiate therapeutic and prophylactic measurements as soon as possible.
Further information here: paraTEST® VET
Instructions for use
16.08.2014 - Study: FASTest® NEOSPORA caninum
MEGACOR Diagnostik GmbH has developed a rapid test for the detection of anti-Neospora caninumNeospora caninum antibodies in whole blood, serum or plasma of dogs and cattle. The test is based on an immunochromatographic reaction, where Neospora caninum antibodies present in the sample are bound to membrane fixed, recombinant Neospora caninum antigens. The interpretation is qualitative. A control line appears confirming the test functionality in principle. In case of a positive sample, an additional Neospora caninum-specific test line appears on the test membrane.
The Institute of Parasitology of Vetsuisse Faculty Bern, Länggass-Str. 122, 3001 Bern was authorized by MEGACOR to run a sensitivity testing of the veterinary test named above. The study contains following issues:
- Check-up of the provided FASTest® NEOSPORA caninum test-kits
- Results of sensitivity testing
- Summary and discussion
Summary and discussion
FASTest® NEOSPORA caninum test-kit is clearly designed. Test procedure is easy and time saving. The test results are qualitative. A quantification of results is not possible. Reading of the test result should be strictly after 15 minutes, due to increasing unspecific reactions between 15 and 20 minutes, respectively, and increase of results that are more difficult to interpret.
In view of the reference lab for neosporosis, FASTest® NEOSPORA caninum test-kit complies to all requirements for a sensitive (relative sensitivity of 96.2%) and specific (relative specificity of 100%) rapid test for the detection of N. caninum in dog and cattle. Unspecific reactions should be clarified with a complementary examination (IFAT, ELISA).
The complete text of the study can be read here.
23.06.2014 - New LEPTOSPIRA IgM antibody rapid test for the dog
New MEGACOR LEPTOSPIRA IgM antibody rapid test
FASTest® LEPTOSPIRA IgM ad us. vet. is an immunochromatographic rapid test for the qualitative detection of Leptospira spp. antibodies in whole blood, plasma or serum of the dog.
Due to the non-existence of a cross immunity of the vaccination serovars and an increasing “serovar shift”, leptospirosis becomes more important (world-wide increasing prevalences especially for L. icterohaemorrhagica, L. canicola, L. grippotyphosa, L. australis and L. pomona).
Incubation time as well as symptoms are strongly dependent on age, immune status and serovar type. Subclinical infections are common and proven by numerous studies proving a higher seroprevalence than the prevalence of the clinical infection.
The actual method of reference, the microagglutination test (MAT), can differentiate between single serovars but has a strongly varying sensitivity (30–80%) depending on infection stadium and does not distinguish between IgM and/or IgG antibodies. Therefore, in the acute phase of leptospirosis a pure IgM proof is a significant diagnostic value.
The FASTest® LEPTOSPIRA IgM is an important diagnostic tool for the veterinarian for the fast and simple on-site detection of a leptospirosis in the early state of infection. Therefore, further laboratory and therapeutic as well as prophylactic measures (zoonosis) can be started immediately.
20.05.2014 - New parasite flotation system: OVATEC® Plus
New distribution product
OVATEC® Plus is a simple, clean and professional fecal testing system with a high accuracy and safety for the identification of parasitic eggs of common gastrointestinal parasites.
The OVATEC® Plus System consists of a zinc sulfate flotation medium which floats parasitic ova (eggs) as well as Giardia cysts, an optimised filter device for improved detection of even low-level ova burdens and an overflow reservoir for the reduction of exposure to potentially hazardous samples.
The OVATEC® Plus System is a client-friendly collection procedure with an easy-to-follow instruction for use and a test device that seals tightly for transport.
28.04.2014 - FASTest® CRYPTO-ROTA D2T
MEGACOR DIAGNOSTIK GmbH expands its FASTest® product portfolio with the rapid test FASTest® CRYPTO-ROTA D2T.
By means of only one test FASTest® CRYPTO-ROTA D2T, the veterinarian is able to aetiologically detect Cryptosporidium parvum and Rotavirus antigens simultaneously in feces of cattle, horse, pig, cat and dog.
Clinically, both diseases cannot be distinguished, and their high infectiosity, the increasing number of co-infections and their high zoonotic potential for humans are reason enough to give an aetiological proof of the pathogen by modern on-site coprodiagnostics.
The FASTest® CRYPTO-ROTA D2T is, similar to the single tests FASTest® CRYPTO Strip and FASTest® ROTA Strip, simple, fast with a test interpretation after 5 minutes and has high sensitivity (C. parvum 94.1% and Rotavirus 96%) and specificity values (C. parvum 95.5% and Rotavirus 100%).
Instructions for use