08.04.2014 - New LEPTOSPIRA IgM antibody rapid test for the dog
FASTest® LEPTOSPIRA IgM ad us. vet. is an immunochromatographic rapid test for the qualitative detection of Leptospira spp. antibodies in whole blood, plasma or serum of the dog.
Leptospirosis is spread world-wide in animals and humans (zoonosis). Due to non-existence of a cross immunity of the vaccination serovars and non-vaccination serovars and an increasing “serovar shift” in recent years, leptospirosis becomes more important.
The symptoms are strongly dependent on age, immune status and serovar type. Apathy, anorexia, vomitus, abdominal pain, diarrhoea, dyspnoea are forerunners, within 48–72 h a serious, partly deathly process can develop, depending on organ manifestation (especially kidneys [tubular persistence], liver and lung [hemorrhagic syndrome] dysfunctions, DIC). Furthermore, there is a shedder and infection risk for humans and animals.
Due to the IgM increase in the first week post infection with detectable IgM in the second week and a maximum from week 2–5 on, the IgM detection must be preferred to the IgG detection (detectable not until 3–4 weeks, persistence for months, vaccination-caused IgG antibody persistence). Because the direct detection of the pathogen often is difficult, time-consuming, expensive and only proving if positive, the IgM antibody detection has an important diagnostic relevance. Therefore, the FASTest® LEPTOSPIRA IgM is an important diagnostic tool for the veterinarian for the fast and simple on-site detection of a leptospirosis in the early stage of infection. Further laboratory diagnostics as well as therapeutic and prophylactic measures can be started immediately.
27.10.2013 - New TOXOPLASMA antibody rapid test for cat & dog
Toxoplasma gondii, agent of toxoplasmosis, plays an important epidemiologic role especially in the cat, but also in the dog. Definite hosts (gamogony and oocysts production) are only cats and other felids (especially lynx, ozelot, puma). The oocysts excreted by the definite host are potentially infectious for humans (zoonosis). Dogs are only intermediate hosts and therefore do not egest oocysts.
Infected animals should be detected, because they are a potential source of infection for humans. Even though only 0.6–1.4 % of cat feces samples in Germany contain oocysts, ca. 70 % of the cats are infected with Toxoplasma.
Approximately 2 weeks post infection, the antibody titre increases (seroconversion) with maximum IgG titres between 2–4 weeks (optimal time point of testing). Thereafter, the titre decreases onto an “infestation titre” (< 1:50), the antibodies can persist. The prevalence for seropositivity (Germany ca. 50–55 %) increases with advanced age.
Clinical symptoms are not pathognomonic in dog and cat and depend on age and immune status of the animal. Seriously acute courses with encephalitis, enteritis, hepatitis, myositis and cell lysis during protozoan propagation mostly lead to death, especially in puppies. In older animals with chronic progression, anorexy, lethargy, fever as well as damage of myocard, liver and CNS are main issues. Main issues in the dog are central nervous disorders ranging from slight malfunction to epileptiform failure.
Because a combination of coprologic and serologic detection (2x at an interval of 14 days) allows direct conclusions on the infection potential of the cat, the veterinarian using FASTest® TOXOPLASMA g is able to identify fast, simple and on-site the T. gondii status of the suspicious animal. This allows to immediately start further diagnostic and therapeutic as well as prophylactic measurements.
Due to similar symptoms of Neosporosis infection, especially young dogs should be differential diagnostically tested with FASTest® NEOSPORA caninum.
Instructions for use
02.08.2013 - New ANAPLASMA antibody rapid test for dog & horse
Anaplasmosis („granulocytotropic ehrlichiosis“) is a bacterial-borne infectious disease vectored by ticks. The agent Anaplasma phagocytophilum plays a future epidemiologic role especially in the dog and in the horse.
As a tick-transmitted (especially Ixodes spp.; Dermacentor spp.) bacterial infectious disease, tick territories (endemic area) should be considered as potential breeding ground for dog and horse. Single infections are usually subclinical and self-limiting. Coinfections are common and can aggravate the course of disease significantly. Here, especially Borrelia infections must be mentioned, particularly as they are transmitted by the same tick species.
Clinical symptoms are fever, apathy, stiff muscle, polyarthritis with joint pain / swelling and lameness as well as weight loss, thrombocytopenia, anaemia, petechial haemorrhages and increasing inflammatory values (CRP, haptoglobin). Subarachnoid haemorrhage could lead to central nervous disorders. Additionally, horses can show metabolic acidosis, oedema, laminitis as well as coffee brown urine.
Antibody titres increase in the first 2–3 weeks post infection and can decrease below the detection limit after 7 months.
Due to similar clinical symptoms in tick-transmitted infectious diseases, the veterinarian using FASTest® ANAPLASMA is able to identify on-site the A. phagocytophilum / A. platys antibody status of the suspicious animal. This enables to start immediately further diagnostic investigations (IFAT, blood smear / count, PCR etc.) as well as prophylactic and therapeutic measurements.
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08.07.2013 - New: FASTest NEOSPORA caninum is now applicable for dog and cattle
New MEGACOR FASTest for Neospora antibodies for DOG & CATTLE
FASTest® NEOSPORA caninum ad us. vet. is an immunochromatographic rapid test for the qualitative detection of anti-Neospora caninum antibodies in whole blood, plasma or serum of the dog and cattle.
Neospora caninum plays an important epidemiologic role in dogs and cattle.The dog (esp. watch dogs, stray dogs) is a definitive host (intestinal neosporosis) and excretes infectious oocysts with the feces. The intermediate host, especially cattle, but also goats, sheep and horse, gets infected via grazing land and / or water contaminated with oocysts (horizontal direct / exogeneous infection) and / or intrauterine via already infected mothers (vertical indirect / endogeneous infection). Both dogs (systemic neosporosis with neuromuscular disorders, myocarditis, hepatitis, pneumonia, dermatitis) and cattle (accumulating abortions in all states of gestation, dead births and weak calves) can develop a clinical disease.
Due to the short excretion period and the low amount of oocysts in dog feces, the detection of antibodies using FASTest® NEOSPORA caninum becomes very important for the diagnosis of neosporosis. Due to horizontal, but particularly to the economical considerably important vertical placental transmission of infection onto the offspring, suspicious cattle stocks should be tested for antibodies against N. caninum using FASTest® NEOSPORA caninum.
16.05.2013 - New: FASTest IgG bovine
New MEGACOR cattle IgG rapid test
FASTest® IgG bovine is an immunochromatographic fast test for the semiquantitative detection of IgG antibodies (immune status) in native blood, whole blood, plasma and serum of cattle.
The immune globulines G (IgG, gamma globulines) belong the the antibody class G mainly directed against viruses and bacteria.
Due to the special placenta conditions, newborn calves show no to hardly noteworthy IgG (especially IgG1) and often show an immune deficiency syndrome (IDS). Therefore, the most important base for an immunoprophylaxis is an adequate supplementation with IgG.
Also, in cows the content of IgG economically plays an important role. If the intrapartal IgG concentration is already significantly decreased (< 15 mg / ml), an increased incidence of genital associated diseases (dystocia, metritis, mastidis a.s.o.) will be seen in the peripartal period.
The optimal test time slot using FASTest® IgG bovine is between 24 to 48 h (max up to 7 days) post natum in calves and from 3rd to 7th day post partum in cows.
FASTest® IgG bovine enables the veterinarian on-farm and withoud any technical costs to confirm (FASTest® IgG bovine: IgG ≤ 12 mg / ml) or to exclude (FASTest® IgG bovine: IgG > 12 mg / ml) a suspicion for FPT / IDS in the cow as well as in the calf.
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21.05.2012 - New: FASTest® CRYPTO-GIARDIA Strip ad us. vet.
MEGACOR DIAGNOSTIK GmbH expands its FASTest® product portfolio with the rapid test FASTest® CRYPTO-GIARDIA Strip. By means of only one test strip FASTest® CRYPTO-GIARDIA Strip, the veterinarian is able to aetiologically detect Cryptosporidium parvum and Giardia duodenalis surface antigens simultaneously in the feces of the dog and/or the cat.
Clinically, both diseases cannot be distinguished, and their high infectiosity, the increasing number of co-infections and their high zoonotic potential for human are reason enough to give an aetiological proof of the pathogen by modern on-site coprodiagnostics.
The FASTest® CRYPTO-GIARDIA Strip is, similar to the single tests FASTest® CRYPTO Strip and FASTest® GIARDIA Strip, simple, fast with a test interpretation after 5 minutes and has high sensitivity (C. parvum 96,7% and G. duodenalis 97,2 %) and specificity values (C. parvum and G. duodenalis 99,9 %).
The compact test boxes (2 or 10 tests, respectively) can be stored at room temperature (15-25°C) up to 24 months after production.
By the simultaneous aetiological proof of the pathogen via FASTest® CRYPTO-GIARDIA Strip, the veterinarian is able to introduce Giardia- and/or Cryptosporidium specific therapy and prophylaxe measures on-site immediately.
Instructions for use
11.01.2012 - New: RIVALTA FIP-VETube ad us.vet.
Simple practical test to detect or exclude FIP infection
The final diagnosis of FIP (Feline Infectious Peritonitis) poses a major diagnostic challenge to the veterinarian. Between diverse methods for the detection of FIP infection, the RIVALTA test is regarded as an important component for the differentiation of transudate (non-inflammable excretion of fluid in body cavities) and exudate (usually inflammatory excretion of fluid in body cavities). Cats suspicious for FIP or with effusion symptoms of unknown origin should be principally aspirated and tested by means of RIVALTA FIP-VETube.
When the exudate suspicious for FIP does contain protein, the punctate drop precipitates during plunging into the aqua-acetic acid mixture. This can be observed by the characteristic formation of more or less stable precipitation products or cloudy mists, forming drops or smears. In contrast, the punctate drop being transudate completely dissolves during sinking in the aqua-acetic acid mixture.
Being fast, simple and reliable, usable on-site and highly significant, the RIVALTA FIP-VETube is an ideal tool to prove or exclude a FIP infection.
The compact test boxes (10 tests per box) are storable at room temperature (15-25° C) for 24 months after production.
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